In 1971, Gabbiani and associates found and characterised the “modification of fibroblasts into cells that are able to an lively spasm” (contraction) in rat wound granulation tissue and, accordingly, named these cells ‘myofibroblasts’. Now, myofibroblasts should not solely acknowledged for his or her physiological function in tissue restore but additionally as cells which might be key in selling the event of fibrosis in all organs. In this Cell Science at a Glance and the accompanying poster, we offer an outline of the present understanding of central features of myofibroblast biology, resembling their definition, activation from completely different precursors, the concerned signaling pathways and most generally used fashions to check their operate. Myofibroblasts…